Stomach Cancer Stage II
Reviewed by Oncology Team, VICI Healthcare | Last updated: 2026-04
What Stage II Means
Moderate-sized tumor involving muscle layer (T3) with no or few lymph nodes involved, or smaller tumor with 3–6 positive nodes (T1-2 N2-3). No metastases.
Treatment Approach for Stage II
Gastrectomy with D2 dissection. Adjuvant chemotherapy with fluoropyrimidine-based regimens strongly recommended for 6 months. Perioperative chemotherapy may be considered.
Survival Rates and Prognosis
The 5-year survival rate for stomach cancer at Stage II is approximately 5-year survival approximately 40–50%. Survival rates are statistical averages drawn from large patient populations and may not reflect your individual outcome. Factors that influence your specific prognosis include your age, overall health, tumour biology, and how well the cancer responds to treatment.
Important: These numbers are drawn from historical data. Newer treatments available today may improve outcomes beyond what published statistics show. Discuss your individual prognosis with your oncologist.
How Other Stages Compare
| Stage | 5-Year Survival | Treatment |
|---|---|---|
| Stage IA | 5-year survival approximately 70–75% | Endoscopic resection for very small lesions, or partial gastrectomy with D2… |
| Stage IB | 5-year survival approximately 60–65% | Subtotal or total gastrectomy with D2 lymph node dissection. Adjuvant… |
| Stage IIIA | 5-year survival approximately 25–35% | Neoadjuvant (preoperative) chemotherapy with FOLFOX or CAPOX for 3 cycles,… |
| IIIB | 5-year survival approximately 15–25% | Perioperative chemotherapy (neoadjuvant and adjuvant FOLFOX/CAPOX). For… |
| Stage IV (Metastatic) | 5-year survival approximately 5–10% (median overall survival 8–14 months with modern therapy) | Palliative chemotherapy with fluoropyrimidine-based regimens (FOLFOX, CAPOX)…. |
Stomach Cancer Treatment in Top Cities
Stomach Cancer in Gurgaon
Stomach Cancer in Noida
Stomach Cancer in Mumbai
Stomach Cancer in Bangalore
Stomach Cancer in Hyderabad
Stomach Cancer in Chennai
Stomach Cancer in Kolkata
Diagnosed with Stage II Stomach Cancer?
Our specialists can review your reports and create a personalised treatment plan.